Overview of Gene Annotation
Gene Annotation is the process by which sequenced DNA is turned into viable information by noting where genes are located. Gene Annotation can be used to determine sex-biased expression (Rogers, R. L., Ling, S. Sanjak, J., Andolfatto, P., and Thornton, K. 2014). This form of annotation has also been used to increase understanding of several others similar species; however, it is only in its primitive phases. Currently, gene annotation requires previous DNA that has already has been annotated with genes. The first fully annotated species is Drosophila melanogaster, which is a fruit fly species that has been the basis for almost all gene annotation. Other species within the Drosophila genus can then be easily annotated because their genes are similar to those of melanogaster. This similarity does not extend to other genera, making it harder to annotate and understand them.
Gene Annotation has also been used to compare melanogaster with other similar species in order to understand the purpose of some proteins, since important proteins are usually conserved across species. Conservation is the idea that the more important the gene, the less likely it will change, because a change to the gene would most likely harm the gene. Because of this, most flies will die if the gene is change, making it conserved. Due to this conservation, prediction programs can use it to determine where genes are located and their similarities.
Gene Annotation is the process by which sequenced DNA is turned into viable information by noting where genes are located. Gene Annotation can be used to determine sex-biased expression (Rogers, R. L., Ling, S. Sanjak, J., Andolfatto, P., and Thornton, K. 2014). This form of annotation has also been used to increase understanding of several others similar species; however, it is only in its primitive phases. Currently, gene annotation requires previous DNA that has already has been annotated with genes. The first fully annotated species is Drosophila melanogaster, which is a fruit fly species that has been the basis for almost all gene annotation. Other species within the Drosophila genus can then be easily annotated because their genes are similar to those of melanogaster. This similarity does not extend to other genera, making it harder to annotate and understand them.
Gene Annotation has also been used to compare melanogaster with other similar species in order to understand the purpose of some proteins, since important proteins are usually conserved across species. Conservation is the idea that the more important the gene, the less likely it will change, because a change to the gene would most likely harm the gene. Because of this, most flies will die if the gene is change, making it conserved. Due to this conservation, prediction programs can use it to determine where genes are located and their similarities.
Statement of Research Problem
There is little data on the relationship between Drosophila melanogaster and Drosophila elegans. These two fruit fly species lie within the same genus and share an interesting trait within the fourth chromosome. An unusual phenomenon occurs where genes that should not be expressed are doing so. Several diseases also cause this phenomenon within humans and by studying this area can help lead to new understanding. As such, the research problem that will be discussed is the relationship between D. elegans and D. melanogaster. By doing so, it is possible to determine the importance of these genes. Overall, by using gene annotation, this study will try to determine the relationship between Drosophila elegans and Drosophila melanogaster.
There is little data on the relationship between Drosophila melanogaster and Drosophila elegans. These two fruit fly species lie within the same genus and share an interesting trait within the fourth chromosome. An unusual phenomenon occurs where genes that should not be expressed are doing so. Several diseases also cause this phenomenon within humans and by studying this area can help lead to new understanding. As such, the research problem that will be discussed is the relationship between D. elegans and D. melanogaster. By doing so, it is possible to determine the importance of these genes. Overall, by using gene annotation, this study will try to determine the relationship between Drosophila elegans and Drosophila melanogaster.